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Multistage analysis method for detection of effective herb prescription from clinical data

Kuo Yang, Runshun Zhang, Liyun He, Yubing Li, Wenwen Liu, Changhe Yu, Yanhong Zhang, Xinlong Li, Yan Liu, Weiming Xu, Xuezhong Zhou, Baoyan Liu

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 206-217 doi: 10.1007/s11684-017-0525-8

Abstract: In this study, a multistage analysis method that integrates propensity case matching, complex networkanalysis, and herb set enrichment analysis was proposed to identify effective herb prescriptions forThen, core network extraction and herb set enrichment were combined to detect core effective herb prescriptionsEffectiveness-based mutual information was used to detect strong herb–symptom relationships.This method was applied on a TCM clinical data set with 955 patients collected from well-designed observational

Keywords： effective prescription detection     herb set enrichment analysis     core network extraction     insomnia     personalized    

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Operating mechanism and set pair analysis model of a sustainable water resources system

Chaoyang DU,Jingjie YU,Huaping ZHONG,Dandan WANG

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 2,   Pages 288-297 doi: 10.1007/s11783-014-0642-4

Abstract: The study introduces a new approach, set pair analysis theory, to measure the state of a SWRS, and anAn evaluation model of the SWRS based on set pair analysis theory is constructed, and an example of SWRS

Keywords： sustainable water resources system     operating mechanism     set pair analysis model     Shanghai    

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Evidence chain-based causality identification in herb-induced liver injury: exemplification of a well-knownliver-restorative herb

Jiabo Wang,Zhijie Ma,Ming Niu,Yun Zhu,Qingsheng Liang,Yanling Zhao,Jingyuan Song,Zhaofang Bai,Yaming Zhang,Ping Zhang,Na Li,Yakun Meng,Qi Li,Lushan Qin,Guangju Teng,Junling Cao,Baosen Li,Shilin Chen,Yonggang Li,Zhengsheng Zou,Honghao Zhou,Xiaohe Xiao

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 457-467 doi: 10.1007/s11684-015-0417-8

Abstract:

Herbal medicines have recently been recognized as the second most common cause of drug-induced liver injury (DILI) in the United States. However, reliable methods to identify the DILI causality of some herbs, such as Heshouwu (dried root of Polygonum multiflorum), remain lacking. In this study, a total of 12 307 inpatients with liver dysfunction and 147 literature-reported cases of Heshouwu DILI were screened. A general algorithm indicated that only 22.5% (9/40) and 30.6% (45/147) of all hospitalization and literature case reports, respectively, demonstrate the high probability of DILI causality of Heshouwu. By contrast, 95% (19/20) of all cases prospectively investigated by pharmacognosy, phytochemistry, and metabolomic tests exhibited highly probable causality, including a patient who was previously incorrectly attributed and a case that was excluded from Heshouwu causality by pharmacognostic evidence. Toxin (heavy metals, pesticides, and mycotoxins) contamination was also excluded from Heshouwu DILI causality. The objectivity of these screening methods for Heshouwu DILI diagnosis addresses safety concerns regarding stilbene-containing herbal medicines and dietary supplements.

Keywords： drug-induced liver injury     pharmacognosy     metabolomics     stilbene     Polygonum multiflorum     Chinese herbal medicine    

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Impact of introducing a herb pasture area into a New Zealand sheep and beef hill country farm system:a modeling analysis

Cécile DURANTON, Cory MATTHEW

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 1,   Pages 87-97 doi: 10.15302/J-FASE-2018202

Abstract: One recent innovation is the introduction of a herb pasture area, such as plantain.

Keywords： farm system configuration     herb pasture     metabolic energy budgeting     plantain     sheep and beef farming    

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Distribution, enrichment mechanism and risk assessment for fluoride in groundwater: a case study of Mihe-Weihe

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 6, doi: 10.1007/s11783-023-1670-8

Abstract:

● High fluorine is mainly HCO3·Cl-Na and HCO3-Na type.

Keywords： the Mihe-Weihe River Basin     Distribution characteristics of fluorine     Factors influencing fluoride     Enrichment    

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Level set-based isogeometric topology optimization for maximizing fundamental eigenfrequency

Manman XU, Shuting WANG, Xianda XIE

Frontiers of Mechanical Engineering 2019, Volume 14, Issue 2,   Pages 222-234 doi: 10.1007/s11465-019-0534-1

Abstract: In this study, we develop an isogeometric analysis (IGA)-based level set model for the formulation andThe proposed method is based on a combination of level set method and IGA technique, which uses the non-uniformrational B-spline (NURBS), description of geometry, to perform analysis.The same NURBS is used for geometry representation, but also for IGA-based dynamic analysis and parameterizationof the level set surface, that is, the level set function.

Keywords： topology optimization     level set method     isogeometric analysis     eigenfrequency    

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Characteristics of plankton Hg bioaccumulations based on a global data set and the implications for aquatic

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 3, doi: 10.1007/s11783-021-1471-x

Abstract:

• Hg bioaccumulation by phytoplankton varies among aquatic ecosystems.

Keywords： Plankton     Hg bioaccumulation     Physiological characteristics     A cross-system analysis     Nutrient compositions     Global data set    

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AGRONOMIC AND ENVIRONMENTAL BENEFITS OF REINTRODUCING HERB- AND LEGUME-RICH MULTISPECIES LEYS INTO ARABLE

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 2,   Pages 245-271 doi: 10.15302/J-FASE-2021439

Abstract:

Agricultural intensification and the subsequent decline of mixed farming systems has led to an increase in continuous cropping with only a few fallow or break years, undermining global soil health. Arable-ley rotations incorporating temporary pastures (leys) lasting 1–4 years may alleviate soil degradation by building soil fertility and improving soil structure. However, the majority of previous research on arable-ley rotations has utilized either grass or grass-clover leys within ungrazed systems. Multispecies leys, containing a mix of grasses, legumes, and herbs, are rapidly gaining popularity due to their promotion in agri-environment schemes and potential to deliver greater ecosystem services than conventional grass or grass-clover leys. Livestock grazing in arable-ley rotations may increase the economic resilience of these systems, despite limited research of the effects of multispecies leys on ruminant health and greenhouse gas emissions. This review aims to evaluate previous research on multispecies leys, highlighting areas for future research and the potential benefits and disbenefits on soil quality and livestock productivity. The botanical composition of multispecies leys is crucial, as legumes, deep rooted perennial plants (e.g., Onobrychis viciifolia and Cichorium intybus) and herbs (e.g., Plantago lanceolata) can increase soil carbon, improve soil structure, reduce nitrogen fertilizer requirements, and promote the recovery of soil fauna (e.g., earthworms) in degraded arable soils while delivering additional environmental benefits (e.g., biological nitrification inhibition and enteric methane reduction). Multispecies leys have the potential to deliver biologically driven regenerative agriculture, but more long-term research is needed to underpin evidence-based policy and farmer guidance.

Keywords： bioactive forages / integrated crop-livestock systems / nitrogen cycling / plant secondary metabolites / soil carbon / soil quality    

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Application of random set method in a deep excavation: based on a case study in Tehran cemented alluvium

Arash SEKHAVATIAN, Asskar Janalizadeh CHOOBBASTI

Frontiers of Structural and Civil Engineering 2019, Volume 13, Issue 1,   Pages 66-80 doi: 10.1007/s11709-018-0461-y

Abstract: excavation in layers of cemented coarse grained soil located in Tehran, Iran by non-deterministic Random Setsimulations simultaneously, without cumbersome procedure of changing input variables in every individual analysisIt was concluded that performing RS analysis before the beginning of every stage could cause great economical

Keywords： uncertainty     reliability analysis     deep excavations     random set method     finite difference method    

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Isogeometric analysis based on geometric reconstruction models

Frontiers of Mechanical Engineering 2021, Volume 16, Issue 4,   Pages 782-797 doi: 10.1007/s11465-021-0648-0

Abstract: In isogeometric analysis (IGA), the boundary representation of computer-aided design (CAD) and the tensor-productnon-uniform rational B-spline structure make the analysis of three-dimensional (3D) problems with irregularIn this paper, an IGA method for complex models is presented by reconstructing analysis-suitable modelsembedded into a regular background grid, and a model reconstruction method is proposed to obtain the level set

Keywords： isogeometric analysis     reconstruction model     level set function     trimmed element     point cloud    

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Geometrically constrained isogeometric parameterized level-set based topology optimization via trimmed

Yingjun WANG,David J. BENSON

Frontiers of Mechanical Engineering 2016, Volume 11, Issue 4,   Pages 328-343 doi: 10.1007/s11465-016-0403-0

Abstract: The isogeometric parameterized level-set-based TO method, which directly uses the non-uniform rationalbasis splines (NURBS) for both level set function (LSF) parameterization and objective function calculation

Keywords： isogeometric analysis     topology optimization     level set method     arbitrary geometric constraint     trimmed element    

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Reliability assessment of three-dimensional bearing capacity of shallow foundation using fuzzy set theory

Rajarshi PRAMANIK, Dilip Kumar BAIDYA, Nirjhar DHANG

Frontiers of Structural and Civil Engineering 2021, Volume 15, Issue 2,   Pages 478-489 doi: 10.1007/s11709-021-0698-8

Abstract: reliability theory on surface square/rectangular footing against bearing capacity failure using fuzzy setof failure is investigated, and the necessity for considering spatial variability in the reliability analysis

Keywords： finite element method     square footing     reliability analysis     fuzzy set theory     coefficient of variation     spatial    

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Sensitivity analysis of torsional vibration behavior of the shafting of a turbo generator set to changes

XIE Danmei, ZHANG Hengliang, DONG Chuan, LIU Zhanhui, YANG Changzhu

Frontiers in Energy 2007, Volume 1, Issue 4,   Pages 483-486 doi: 10.1007/s11708-007-0072-4

Abstract: Aiming at a 300 MW turbo-generator model, the sensitivity of natural torsional frequencies and modes of torsional vibration (TV) to the rotational inertia and stiffness of the turbo-generator were analyzed. Calculation results show

Keywords： Calculation     MW turbo-generator     sensitivity     stiffness    

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An enhanced environmental multimedia modeling system based on fuzzy-set approach: II.

Rongrong ZHANG,Chesheng ZHAN,Xiaomeng SONG,Baolin LIU

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 6,   Pages 1025-1035 doi: 10.1007/s11783-014-0655-z

Abstract: I of this study develops an enhanced environmental multimedia modeling system (EMMS) based on fuzzy-setIn addition, with the aid of fuzzy-set approach, EMMS can be a reliable and powerful tool to address

Keywords： environmental multimedia modelling system     fuzzy-set approach     application     model validation     uncertaintyanalysis    

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Water Diversion is Not to Blame for Phosphorus Enrichment in Taihu Lake

Zhiyuan Wang,Qiuwen Chen,Jianyun Zhang,Hanlu Yan,

Engineering doi: 10.1016/j.eng.2023.07.007

Abstract: The Water Diversion Project from the Yangtze River to Taihu Lake (WDYT) has been widely recognized as an urgent and effective engineering measure to increase water resources, ameliorate the hydrodynamics and water quality conditions, and safeguard the water supply of Taihu Basin. However, some previous studies claimed that WDYT has brought in allochthonous nutrients and should take responsibility for the dramatic increase in phosphorus loading of Taihu Lake in recent years, because Yangtze River has a higher average phosphorus concentration than Taihu Lake. To ensure correct public understanding and provide a critical response to the misconception about the source of phosphorus loading, we quantified contribution of water diversion from the Yangtze River to phosphorus loadings of Taihu Lake over the past twenty years. We reveal that WDYT only diverted 4.3% annually of total phosphorus input of Taihu Lake in the last decade and should not be responsible for the increase in phosphorus concentration and loading in Taihu Lake. We conclude that phosphorus input from the Huxi Region contribute 78% of phosphorus input of Taihu Lake and should be primarily responsible for the high phosphorus concentration of Taihu Lake. Our findings have provided constructive guidance for water resource management of Taihu Basin and phosphorus load control of the second stage of WDYT.
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Title Author Date Type Operation

Multistage analysis method for detection of effective herb prescription from clinical data

Kuo Yang, Runshun Zhang, Liyun He, Yubing Li, Wenwen Liu, Changhe Yu, Yanhong Zhang, Xinlong Li, Yan Liu, Weiming Xu, Xuezhong Zhou, Baoyan Liu

Journal Article

Operating mechanism and set pair analysis model of a sustainable water resources system

Chaoyang DU,Jingjie YU,Huaping ZHONG,Dandan WANG

Journal Article

Evidence chain-based causality identification in herb-induced liver injury: exemplification of a well-knownliver-restorative herb

Jiabo Wang,Zhijie Ma,Ming Niu,Yun Zhu,Qingsheng Liang,Yanling Zhao,Jingyuan Song,Zhaofang Bai,Yaming Zhang,Ping Zhang,Na Li,Yakun Meng,Qi Li,Lushan Qin,Guangju Teng,Junling Cao,Baosen Li,Shilin Chen,Yonggang Li,Zhengsheng Zou,Honghao Zhou,Xiaohe Xiao

Journal Article

Impact of introducing a herb pasture area into a New Zealand sheep and beef hill country farm system:a modeling analysis

Cécile DURANTON, Cory MATTHEW

Journal Article

Distribution, enrichment mechanism and risk assessment for fluoride in groundwater: a case study of Mihe-Weihe

Journal Article

Level set-based isogeometric topology optimization for maximizing fundamental eigenfrequency

Manman XU, Shuting WANG, Xianda XIE

Journal Article

Characteristics of plankton Hg bioaccumulations based on a global data set and the implications for aquatic

Journal Article

AGRONOMIC AND ENVIRONMENTAL BENEFITS OF REINTRODUCING HERB- AND LEGUME-RICH MULTISPECIES LEYS INTO ARABLE

Journal Article

Application of random set method in a deep excavation: based on a case study in Tehran cemented alluvium

Arash SEKHAVATIAN, Asskar Janalizadeh CHOOBBASTI

Journal Article

Isogeometric analysis based on geometric reconstruction models

Journal Article

Geometrically constrained isogeometric parameterized level-set based topology optimization via trimmed

Yingjun WANG,David J. BENSON

Journal Article

Reliability assessment of three-dimensional bearing capacity of shallow foundation using fuzzy set theory

Rajarshi PRAMANIK, Dilip Kumar BAIDYA, Nirjhar DHANG

Journal Article

Sensitivity analysis of torsional vibration behavior of the shafting of a turbo generator set to changes

XIE Danmei, ZHANG Hengliang, DONG Chuan, LIU Zhanhui, YANG Changzhu

Journal Article

An enhanced environmental multimedia modeling system based on fuzzy-set approach: II.

Rongrong ZHANG,Chesheng ZHAN,Xiaomeng SONG,Baolin LIU

Journal Article

Water Diversion is Not to Blame for Phosphorus Enrichment in Taihu Lake

Zhiyuan Wang,Qiuwen Chen,Jianyun Zhang,Hanlu Yan,

Journal Article